Howdy,
Well, I hadn't run into that before, that's an interesting error ;-)
It looks like you saw this too, but for the sake of anyone reading this later, the error is described here:
http://httpd.apache.org/docs/2.0/faq/error.htmlIf you go by that, it sounds pretty cut and dry that you should disable MMAP and Sendfile as you suggested.
OTOH, this link suggests it could be from a misconfigured Apache directive:
http://www.howtoforge.com/forums/showthread.php?t=14125So my gut feeling on it is that you should verify the directives for the Virtual Server in question ... and if you don't see anything out of place or incorrect, it seems fairly safe to disable those options.
Good luck!
-Eric