Howdy Ronald,
Well, that depends on whether this is a two-way mailing list (i.e. one that all subscribers can respond to and discuss topics with each other), or just a simple mail list that you blast a message out to periodically. For the former, Virtualmin supports the creation and management of the Mailman mailing list manager. For the latter, you'll want to try PHPList. It's included in the Install Scripts interface, so should be simple to install.
It is documented on the PHPList home page, at
http://www.phplist.com/Holler if you run into any trouble getting things spinning. I've never actually used PHPList, beyond a test install or two, but it came highly recommended from a few customers who use it for their newsletters.